Therapeutic beneficence and patient recruitment in randomized controlled clinical trials.
نویسنده
چکیده
منابع مشابه
درماتولوژی مبتنی بر شواهد: گزارش درست مقایسهی پیامدها در کارآزماییهای بالینی
According to evidence-based medicine, randomized controlled clinical trials are a group of research designs which provides the highest level of clinical evidence, particularly regarding therapeutic or preventive interventions. Considering the dramatic increase in the number of published clinical trials in medical journals, the readership need to have knowledge about the problems that may occur ...
متن کاملBlindness in Randomized Controlled Trials
In combination with randomization, blinding or masking is an important factor in randomized controlled trials (RCTs), particularly in trials that assess therapeutic effects. Here an attempt is made to explain blindness and why it is important. In clinical trials, blinding is defined as the condition imposed on a study in which study participants, health care providers and assessors collecting o...
متن کاملEvaluation of the Quality of Writing of the Title and Abstract of Randomized Controlled Clinical Trial Papers Published in the Journals of the Iran,s Universities of Medical Sciences in 2016, Based on the CONSORT Checklist: A Descriptive Study
Background and Objectives: Given the fact that randomized controlled clinical trials are more valid than other research methods to determine the therapeutic effects of treatment, proper design and accurate reporting is of particular importance. This study was conducted with the aim of evaluating the quality of writing the title and abstract of randomized clinical trials of Iranian medical unive...
متن کاملEvaluation of Clinical Trials
In a number of important clinical issues such as evaluation of the efficacy or effectiveness of therapeutic or preventive interventions as well as for comparing the harms of interventions, randomized controlled trials (RCTs) provide the highest levels of evidence, either directly or indirectly. It is obvious that critical appraisal of these studies to assess their validity and precision is of p...
متن کاملChoosing a control intervention for a randomised clinical trial
BACKGROUND Randomised controlled clinical trials are performed to resolve uncertainty concerning comparator interventions. Appropriate acknowledgment of uncertainty enables the concurrent achievement of two goals : the acquisition of valuable scientific knowledge and an optimum treatment choice for the patient-participant. The ethical recruitment of patients requires the presence of clinical eq...
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عنوان ژورنال:
- The American journal of bioethics : AJOB
دوره 2 2 شماره
صفحات -
تاریخ انتشار 2002